Laryngo-Pharyngeal Reflux/Silent Reflux
What is LPR?
Laryngo-Pharyngeal Reflux is also known as LPR and Silent Reflux. The terms are interchangeable and you'll see all three used on this site. They have the same meaning.
There remains dispute among doctors as to what exactly LPR is and some even doubt its existence. There is no accepted scientific definition and it can be very difficult to both diagnose and treat. Symptoms associated with LPR are however probably just as common as the heartburn/indigestion types and can be severe enough to blight some patients’ lives. Because so much remains unknown about LPR and the tests required to make the right diagnosis are not generally available, people often find themselves in what we call a “Cycle of Frustration”. However, since we see so many patients with LPR, as well as other reflux type symptoms, we have enormous experience and by using the RefluxUK MDT approach, as well as the most up to date tests and treatment technologies we can achieve a good outcome for most people.
There are many symptoms of Silent Reflux and patients may have several or just one. Symptoms include:
- Sore throat; sometimes persistent, sometimes worse in the morning.
- Voice problems: people can report huskiness or weakness of the voice and singers difficulty hitting the right notes.
- Cough; can occur at night or after eating. Sometimes can respond to anti-acids but if it doesn’t that doesn’t mean it’s not caused by reflux as it may be non-acidic reflux.
- Throat clearing/mucous and post-nasal drip. Can often be the most troubling and patients often report that their partners complain about this. They describe a constant feeling of mucous in the throat and having to clear this. Can then proceed to a sore throat.
- Globus; a feeling of a lump in the throat.
- Sinus problems; often patients will have been diagnosed with sinus problems and even have undergone surgery in the past.
- Bad breath.
- Nasty taste/tingling lips.
Get your LPR score
Measure the strength of your LPR symptoms by using our Reflux Symptom Checker. You'll be able to see your LPR 'score' using a scientifically validated questionnaire. We'll also send you a personalised report based on your results.
Start Symptom Checker
What Causes LPR?
It’s likely that LPR can be caused by different problems and may well be more complex than simple acid reflux.
- Poorly functioning Lower Oesophageal Sphincter (LOS); it’s failure, often but not always associated with a hiatus hernia, will allow reflux of stomach contents up to the throat. This can be in either liquid or aerosol/gaseous form and will cause local irritation or cause a nervous reflex for instance causing a cough and is probably the most common cause of all types of reflux symptoms.
- Gastroparesis / poor gastric emptying; if the stomach doesn’t empty properly either because of poor motility or a functional blockage then the pressure inside the stomach will exceed the LOS pressure causing reflux symptoms. Its literally like a damn across a river causing upstream pressure. In the case of gastroparesis in which the stomach nervous and muscular activity decreases symptoms can have a very sudden onset as it’s thought that viral infections particularly in young people are a common cause. Research also suggests that in some people there is a failure of the valve at the bottom of the stomach, the pylorus, to relax properly. In this case the stomach can’t empty properly as there is a functional blockage rather than poor muscular contraction.
- Small Intestinal Bacterial Overgrowth (SIBO); Overgrowth of the small bowel by organisms that digest carbohydrates and produce gas can cause excessive belching/burping which in turn will cause reflux of gaseous reflux to the throat. Since (SIBO) can develop rapidly, LPR symptoms caused by SIBO can also be of rapid onset. When treated with Proton Pump Inhibitors (PPIs) LPR symptoms caused by SIBO may well get even worse as PPIs are associated with this condition.
- Low stomach acid; There are some authors that blame reflux on low stomach acid and suggest taking additional acid as a treatment. However, there is currently no scientific evidence to support this theory.
- Oesophageal Inlet patch; there is evidence that in some patients a small patch of acid secreting tissue at the top of the oesophagus can cause irritation of the adjacent larynx and pharynx. In these patients this is probably an embryological remnant. Research of this condition is on-going.
- Upper oesophageal sphincter (UOS) dysfunction; the valve at the top of the oesophagus can become over-active in response to a failing LOS in an attempt to protect the airway. This may be responsible for LPR symptoms such as Globus. However, the role of the UOS in LPR remains unclear.
Getting an accurate diagnosis of your LPR is essential. The tests we use will enable us to do this for you and will also inform your treatment plan. Read more about how we diagnose LPR and the tests we use here.
LPR Treatment Success Stories
If you are suffering with the symptoms of LPR, don't despair, it can be treated. We have collected some stories of people we have successfully treated. You may recognise the cycle of frustration they experienced while trying to get an accurate diagnosis. We were able to provide this diagnosis and an effective treatment plan.
Read their inspiring stories here.
Here, Cutting Crew singer and composer Nick van Eede talks about how LINX®️ surgery helped prolong his singing career.
Treatment of LPR can be one of the most difficult challenges we face. In the first instance it's imperative to make the correct diagnosis and identify the underlying cause. In general, we would escalate treatment from simple towards more complex dependent upon response and patient preference
Page reviewed by:
Mr Nicholas Boyle BM MS FRCS